Although it may not be obvious here, I also occasionally write formal scientific stuff, like a review article for Trends in Genetics:
Abstract
Alternative splicing is a highly regulated process that greatly increases the proteome diversity and plays an important role in cellular differentiation and disease. Interactions between RNA-binding proteins (RBPs) and pre-mRNA are the principle regulator of splicing decisions. Findings from recent genome-wide studies of protein-RNA interactions have been combined with assays of the global effects of RBPs on splicing to create RNA splicing maps. These maps integrate information from all pre-mRNAs regulated by single RBPs to identify the global positioning principles guiding splicing regulation. Recent studies using this approach have identified a set of positional principles that are shared between diverse RBPs. Here, we discuss how insights from RNA splicing maps of different RBPs inform the mechanistic models of splicing regulation.
Congratulations! The whole process seems to have gone quickly for you… I wish I could say the same for my paper.
You should do more than just tease with the abstract – blog about the review, using a Rugby analogy to explain the behavior of RBPs.
I may follow up. This method did not require time, that precious commodity, ever so rare and valuable.
We started writing in July & I have approximately 29 revised drafts on my hard drive. So, quickly is in the eye of the beholder; but I know what you are saying. Of course, the process is different with review articles where you don’t actually have to generate your own data.
I was under the mistaken impression that you had started writing later. I didn’t start writing until October. We are now up to draft 20 or so, hoping against the odds that Science will find this latest version acceptable.