For my entire scientific career, I’ve introduced every talk with one of the following arguments:
1) G-protein coupled receptors are fundamentally important and interesting because they are involved in almost every aspect of our physiology, and because they are the targets of the majority of currently used drugs.
2) Gene regulation is fundamentally important and interesting because it is involved in almost every major biological process, including development, cell division, and differentiation, as well as disease.
Now I can skip all that and say:
1) GPCRs are important and interesting, and the Nobel Prize for Lefkowitz and Kobilka proves the Swedish Academy agrees with me.
2) Gene regulation is important and interesting, and the Nobel Prize shared by Yamankana proves the Swedish Academy agrees with me.
My hearty congratulations to the winners.